Data sharing in stepped-wedge cluster randomized trials: suboptimal data availability despite "data available upon request".

Cory E. Goldstein, A. Armond, K. Cobey, E. Voldal, Yutong Chen, Kylie Tingley, Julia F. Shaw, P. Heagerty, K. Hemming, Avi Kenny, Fan Li, Yongdong Ouyang, Fan Xia, David Moher, James P. Hughes, M. Taljaard

Journal of Clinical Epidemiology, 2026

Which Small-Sample Correction Should Be Used When Analyzing Stepped-Wedge Designs with Time-Varying Treatment Effects?

Yongdong Ouyang, M. Taljaard, James P Hughes, Fan Li

2026

Evaluation of injury prevention interventions using the stepped wedge cluster randomised trial design: key considerations

Yongdong Ouyang, Christian Vaillancourt, Anna Heath, M. Taljaard, Colin Macarthur

Injury Prevention, 2025

A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials

Guangyu Tong, Pascale Nevins, Mary M Ryan, Kendra Davis-Plourde, Yongdong Ouyang, J. P. Pereira Macedo, C. Meng, Xueqi Wang, Agnès Caille, Fan Li, Monica Taljaard

Clinical Trials, 2024

Estimates of intra-cluster correlation coefficients from 2018 USA Medicare data to inform the design of cluster randomized trials in Alzheimer’s and related dementias

Yongdong Ouyang, Fan Li, Xiaojuan Li, Julie P. W. Bynum, V. Mor, Monica Taljaard

Trials, 2024

Accounting for complex intracluster correlations in longitudinal cluster randomized trials: a case study in malaria vector control

Yongdong Ouyang, M. Kulkarni, Natacha Protopopoff, Fan Li, M. Taljaard

BMC Medical Research Methodology, 2023

Adherence to key recommendations for design and analysis of Stepped-Wedge Cluster Randomized Trials: A Review of trials published 2016–2022

Pascale Nevins, Mary M Ryan, Kendra Davis-Plourde, Yongdong Ouyang, J. P. Pereira Macedo, C. Meng, Guangyu Tong, Xueqi Wang, Luis Ortiz-Reyes, Agnès Caille, Fan Li, Monica Taljaard

Clinical Trials, 2023

A scoping review described diversity in methods of randomization and reporting of baseline balance in stepped-wedge cluster randomized trials

Pascale Nevins, Kendra Davis-Plourde, J. P. Macedo, Yongdong Ouyang, Mary M Ryan, Guangyu Tong, Xueqi Wang, C. Meng, Luis Ortiz-Reyes, Fan Li, A. Caille, M. Taljaard

Journal of Clinical Epidemiology, 2023

Does it decay? Obtaining decaying correlation parameter values from previously analysed cluster randomised trials

J. Kasza, R. Bowden, Yongdong Ouyang, M. Taljaard, A. Forbes

Statistical Methods in Medical Research, 2023

Estimating intra-cluster correlation coefficients for planning longitudinal cluster randomized trials: a tutorial.

Yongdong Ouyang, K. Hemming, Fan Li, M. Taljaard

International Journal of Epidemiology, 2023

Maintaining the validity of inference from linear mixed models in stepped-wedge cluster randomized trials under misspecified random-effects structures

Yongdong Ouyang, M. Taljaard, A. Forbes, Fan Li

Statistical Methods in Medical Research, 2023

Sample size calculators for planning stepped-wedge cluster randomized trials: a review and comparison.

Yongdong Ouyang, Fan Li, J. Preisser, M. Taljaard

International Journal of Epidemiology, 2022

CRTpowerdist: An R package to calculate attained power and construct the power distribution for cross-sectional stepped-wedge and parallel cluster randomized trials

Yongdong Ouyang, Liang Xu, M. E. Karim, P. Gustafson, H. Wong

Comput. Methods Programs Biomed., 2021

Methods for dealing with unequal cluster sizes in cluster randomized trials: A scoping review

Denghuang Zhan, Liang Xu, Yongdong Ouyang, R. Sawatzky, H. Wong

PLoS ONE, 2021

Explaining the variation in the attained power of a stepped-wedge trial with unequal cluster sizes

Yongdong Ouyang, M. E. Karim, P. Gustafson, Thalia Shoshana Field, H. Wong

BMC Medical Research Methodology, 2020

The randomization-induced risk of a trial failing to attain its target power: assessment and mitigation

H. Wong, Yongdong Ouyang, M. E. Karim

Trials, 2019

Adjusting for intercurrent events using Bayesian joint models for longitudinal outcomes in clinical trials.

Wen Teng, Yongdong Ouyang, J. Dianti, Niall D. Ferguson, E. Goligher, Anna Heath

Contemporary Clinical Trials Communications, 2026

Remote, bivariate prior elicitation for a Bayesian non-inferiority randomized controlled trial.

Arlene Jiang, A. Aregbesola, Apoorva Gangwani, Terry P. Klassen, Amy C. Plint, Elisabete Doyle, William Raine Craig, Mohamed Eltorki, B. Oketola, H. Badran, Yongdong Ouyang, Anna Heath

Trials, 2026

A systematic review of sample size determination in Bayesian randomized clinical trials: full Bayesian methods are rarely used

Yanara Marks, Jessie Cunningham, Arlene Jiang, Linke Li, Yi-Shu Lin, Abigail McGrory, Yongdong Ouyang, Nam-Anh Tran, Yuning Wang, A. Heath

BMC Medical Research Methodology, 2025

Bayesian adaptive enrichment design in multi-arm clinical trials: The BayesAET package for R users

Denghuang Zhan, Yongdong Ouyang, F. Vila-Rodriguez, Mohammad Ehsanul Karim, Hubert Wong

Comput. Methods Programs Biomed., 2025

Bayesian Analysis of Time-To-Event Data in a Cluster-Randomized Trial: Major Outcomes With Personalized Dialysate TEMPerature (MyTEMP) Trial

Yongdong Ouyang, Bin Luo, Stephanie N. Dixon, Ahmed A. Al-Jaishi, P. J. Devereaux, Michael Walsh, Ron Wald, Merrick Zwarenstein, Sierra Anderson, Amit X. Garg

Canadian Journal of Kidney Health and Disease, 2025

Using Bayesian pre-trial simulations to optimize the design of adaptive clinical trials in childhood nephrotic syndrome.

Cal H. Robinson, Rulan S Parekh, Brian H. Cuthbertson, E. Fan, Yongdong Ouyang, Anna Heath

Contemporary Clinical Trials, 2025

Who benefits? Uncovering hidden heterogeneity of treatment effects in adaptive trials using Bayesian methods: a systematic review

Rachel Giblon, Chengyang Gao, Kuan Liu, Yongdong Ouyang, Jessie Cunningham, Allen L. Pimienta, E. Goligher, Anna Heath

Trials, 2025

Priors from Envisioned Posterior Judgments: A Novel Elicitation Approach With Application to Bayesian Clinical Trials

Yongdong Ouyang, Janice J Eng, Denghuang Zhan, Hubert Wong, The WnW Research Team

2024

Using Simulation to Optimize the Design of Adaptive Clinical Trials

Cal H. Robinson, Rulan S Parekh, Brian H. Cuthbertson, E. Fan, Yongdong Ouyang, Anna Heath

Journal of the American Society of Nephrology, 2024

Improving efficiency in the stepped-wedge trial design via Bayesian modeling with an informative prior for the time effects

Denghuang Zhan, Yongdong Ouyang, Liang Xu, H. Wong

Clinical Trials, 2021

Adjuvant chemotherapy versus chemoradiotherapy in high-risk extrahepatic cholangiocarcinoma and gallbladder carcinoma: A National Database analysis.

V. Muthusamy Kumarasamy, Yongdong Ouyang, Kayla Catalfamo, V. Deenadayalan, Archit Patel, Z. Stiles, M. Dhir, Leonid Cherkassky, Kannan Thanikachalam

Journal of Clinical Oncology, 2026

Age-stratified evaluation of subsequent primary malignancy risk in patients with primary Lynch syndrome–spectrum cancers.

Vinit Singh, Yongdong Ouyang, S. Surpur, Sarbajit Mukherjee, X. Llor, D. Vadehra

Journal of Clinical Oncology, 2026

Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in malignant peritoneal mesothelioma (MPM).

Kriti Ahuja, V. Deenadayalan, Yongdong Ouyang, Mrinalini Ramesh, Kannan Thanikachalam

Journal of Clinical Oncology, 2026

Neoadjuvant chemotherapy with or without radiation versus upfront esophagectomy in small cell carcinoma of the esophagus: A national database analysis of overall survival.

V. Muthusamy Kumarasamy, V. Deenadayalan, Yongdong Ouyang, Kayla Catalfamo, M. Kukar, Z. Stiles, M. Dhir, Kannan Thanikachalam

Journal of Clinical Oncology, 2026

Patterns and incidence of brain metastases in high-grade neuroendocrine carcinomas.

Reem Dergham, Yongdong Ouyang, Megan Wansart, Renuka Iyer, Prantesh Jain

Journal of Clinical Oncology, 2026

Real-world outcomes with elotuzumab, lenalidomide, and dexamethasone in patients progressing on lenalidomide maintenance therapy: A single-center retrospective analysis

Zunairah Shah, Ian Lund, Sarah Parker, Kimberly Celotto, Kristina Slemmer, Hailey Battaglia, Megan Schaefer, Yongdong Ouyang, Hamza Hassan, Jens Hillengass

Blood, 2025

Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (the PROMIZING study): update to the statistical analysis plan for a randomized controlled trial

Karen J. Bosma, M. Lafreniere-Roula, Arlene Jiang, Anna Heath, Yongdong Ouyang, Kaitlyn E Wade, Pingzhao Hu, Karen E A Burns, Claudio M Martin, Y. Skrobik, Sorcha Mulligan, Kevin E Thorpe, L. Brochard, Andre Carlos Kajdacsy-Balla John Jason Alain François Ga Amaral Basmaji Shahin Mercat Beloncle Beduneau Des, Andre Amaral, J. Basmaji, Jason Shahin, A. Mercat, F. Beloncle, G. Béduneau, A. Dessap, G. Carteaux, Alexandre Demoule, Marie Lecronier, M. Dres, K. Vaporidi, E. Kondili, V. Fanelli, S. Spadaro, Y. Arabi, J. Mancebo Cortés, J. C. Montero, I. M. Chorro, Nuria Farré, François Lellouche, P. O. Rodriguez, Jeff M Singh, M. E. Wilcox, T. Maraffi, Emmanuel Charbonney, Stephanie Sibley, E. Goligher, Niall D. Ferguson, Anna Geagea, Phil Shin, I. Telias, Christopher J Yarnell, Gabriela Ferreyra, Hiba Azher, Cheryl Misak

Trials, 2024

A Hospital-Wide Open-Label Cluster Crossover Pragmatic Comparative Effectiveness Randomized Trial Comparing Normal Saline to Ringer’s Lactate: Protocol and Statistical Analysis Plan of The FLUID Trial

Julia F. Shaw, Yongdong Ouyang, D. Fergusson, T. McArdle, C. Martin, Deborah J Cook, Ian D. Graham, S. Hawken, Colin J L McCartney, K. Menon, R. Saginur, A. Seely, I. Stiell, A. Fox-Robichaud, Shane English, J. Marshall, K. Thavorn, M. Taljaard, Lauralyn A McIntyre

JMIR Research Protocols, 2023

Cervical spine injuries in adults ≥ 65 years after low-level falls - A systematic review and meta-analysis.

J. McCallum, D. Eagles, Yongdong Ouyang, Jamie Vander Ende, C. Vaillancourt, C. Fehlmann, R. Shorr, M. Taljaard, I. Stiell

American Journal of Emergency Medicine, 2023

Duration of Adjunctive Antidepressant Maintenance in Bipolar I Depression.

L. Yatham, S. Arumugham, M. Kesavan, K. Ramachandran, Nithyananda S Murthy, G. Saraf, Yongdong Ouyang, D. Bond, A. Schaffer, A. Ravindran, N. Ravindran, B. Frey, A. Daigneault, S. Beaulieu, R. Lam, Nithin Kondapuram, M. S. Reddy, R. Bhandary, Mysore V Ashok, Kyooseob Ha, Y. Ahn, R. Milev, H. Wong, Y. Reddy

New England Journal of Medicine, 2023

Evaluating the effectiveness of a multifaceted intervention to reduce low-value care in adults hospitalized following trauma: a protocol for a pragmatic cluster randomized controlled trial

L. Moore, M. Bérubé, A. Belcaid, A. Turgeon, M. Taljaard, Robert Fowler, N. Yanchar, É. Mercier, J. Paquet, H. Stelfox, P. Archambault, S. Berthelot, J. Guertin, Barbara Haas, N. Ivers, J. Grimshaw, Alexandra Lapierre, Yongdong Ouyang, Michael Sykes, H. Witteman, P. Lessard-Bonaventure, B. Gabbe, F. Lauzier

Implementation Science, 2023

Control of Line Complications with KiteLock (CLiCK) in the critical care unit: study protocol for a multi-center, cluster-randomized, double-blinded, crossover trial investigating the effect of a novel locking fluid on central line complications in the critical care population

M. Ornowska, H. Wong, Yongdong Ouyang, A. Mitra, Aaron P. White, S. Willems, J. Wittmann, S. Reynolds

Trials, 2022

The impact of learner involvement in emergency department patient assessments on short-term return visits requiring hospital admission: a cross-sectional study

Kuan-chin Jean Chen, C. Elliott, M. Nemnom, Yongdong Ouyang, T. Fitzpatrick

Canadian Journal of Emergency Medicine, 2022

Design and analysis of individually randomized multiple baseline factorial trials

Yongdong Ouyang, M. L. Avila, Anna Heath

Behavior Research Methods, 2026

Reporting of and explanations for under-recruitment and over-recruitment in pragmatic trials: a secondary analysis of a database of primary trial reports published from 2014 to 2019

Pascale Nevins, S. Nicholls, Yongdong Ouyang, Kelly Carroll, K. Hemming, C. Weijer, M. Taljaard

BMJ Open, 2022

Increasing the power of randomized trials comparing different treatment durations

Yongdong Ouyang, H. Qian, L. Yatham, H. Wong

Contemporary Clinical Trials Communications, 2020